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Clinical & Translational Research at UNC Chapel-Hill

March 2, 2021

The NIH-funded NC TraCS Institute at UNC is a CTSA hub founded as a service to the research community— guiding investigators and study teams through clinical trials and regulatory approval, all the way to implementation in patient care.

Carolina Awarded $2.91 Million to Create New Ultra-long-acting HIV Drug Delivery Implant

November 6, 2019

HIV clinical trials have shown that the protective efficacy of daily antiretroviral drugs for the prevention of HIV transmission correlates with adherence – whether an uninfected person takes the prescribed medication at proper times. But nonadherence is a major roadblock toward decreasing the spread of HIV. One solution to the adherence problem is to make drug delivery less frequent but no less effective.

AnelleO: 3D Printing to Create Devices for HIV Prevention, Birth Control and Infertility

November 3, 2019

Women and girls are disproportionately affected by the HIV/AIDS epidemic, comprising more than half of the estimated 37.9 million people living with the disease. Moreover, according to United Nations AIDS, some regions of the world, like sub-Saharan Africa, have an even higher burden, with women and girls constituting over 57% of the affected population, compared to 52% worldwide. With an unwavering increase of the disease along with antiretroviral treatments that can only help control the virus, not kill it, preventing HIV infection is essential. Researchers have been investigating for many years the use of intravaginal rings (IVRs) as devices for the delivery of agents to protect against the sexual transmission of HIV and other diseases, as well as to prevent unwanted pregnancies.

HIV Drug Delivery Made Easier with Long-Acting Implant

September 23, 2019

Adherence to a strict HIV regimen is an essential part of effective HIV treatment. Medication should be taken every day, at specific times of the day, and with or without certain kinds of food. Making this process easier would, undoubtedly, increase medication adherence and improve the efficacy of current HIV treatment plans.

Personalized Drug Delivery in 3D

September 15, 2019

On a mission for innovation and translational science, Rahima Benhabbour is using 3D-printing technology and her startup company AnelleO to create a breakthrough in women’s health.

Carolina Stories

April 15, 2019

Dr. Soumya Rahima Benhabbour is from the North African country of Morocco where, according to UNAIDS, there has been a 42 percent reduction in new HIV infections since 2010.

That’s good news to Benhabbour, whose dream is to empower women and those in greatest need.