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3D Printed Intravaginal Ring (IVR) Platform Technology – Next Generation Multipurpose Prevention Technology (MPT) IVRs

Our lab is pioneering the development of the next generation MPT IVR that is prospectively conceived, designed, constructed, tested and manufactured, in a rational development path that implements state of the art drugs, materials, performance evaluation and manufacturing methods. Particular advantages to our device and methodology are: 1) it is manufactured using state-of-the-art 3D Continuous Liquid Interface Production (CLIP™) printing; this enables diverse device geometry and biophysical properties, efficient drug loading & controlled release, and sound, automated manufacturing with good process control; 2) use of a proprietary drug loading process disassociated from the fabrication process to allow formulation of a wide range of drugs including biologics. These IVRs are currently being develop as the next generation MPT for prevention of HIV, HSV, and unplanned pregnancy.

Rima Janusziewicz, Sue J. Mecham, Kevin R. Olson, S. Rahima Benhabbour*. Design and Characterization of a Novel Series of Geometrically Complex Intravaginal Rings with Digital Light Synthesis, Advanced Materials Technologies, 2020, 2000261, 1-16, DOI: 10.1002/admt.202000261.